2. Signaling Pathways
  3. Neuronal Signaling
  4. Serotonin Transporter
  5. Serotonin Transporter Modulator

Serotonin Transporter Modulator

Serotonin Transporter Modulators (4):

Cat. No. Product Name Effect Purity
  • HY-169394
    5-HT1AR agonist 2
    		Modulator
    5-HT1AR agonist 2 (Compound 4f) is a 5-HT1A receptor agonist (Ki: 10.0 nM). 5-HT1AR agonist 2 also binds to the SERT, D2 receptor and 5-HT6 receptor (Ki: SERT, 2.8 nM; D2, 23 nM; 5-HT6, 192 nM). 5-HT1AR agonist 2 is stabilized in microsomes and induces hypothermia in mice.
  • HY-N10588A
    Nardoguaianone J
    		Modulator
    Nardoguaianone J, a guaiane-type compound, can be isolated from Nardostachys chinensis roots. Nardoguaianone J can enhance SERT activity.
  • HY-W009681
    1-(2-Methoxyphenyl)piperazine hydrochloride
    		Modulator
    1-(2-Methoxyphenyl)piperazine hydrochloride is a key agent intermediate of antipsychotics with high affinity to the serotonin receptors and 5-HT, which can be used to synthesize the intestinal worm-repellent agents Piperazine phosphate (HY-B0912C) and Piperazine citrate (HY-17599), as well as Fluphenazine (HY-119980), dihydrochloride, Rifampicin (HY-B0272).
  • HY-125932A
    9β-Debilon
    		Modulator
    9β-Debilon is a sesquiterpenoid compound found in Nardostachys chinensis and may possess SERT regulatory activity. Structurally, 9β-Debilon is a diastereomer of Debilon (HY-125932). 9β-Debilon holds potential for research into neurological disorders.